Animal Models of Adrenocortical Tumorigenesis

Publication date

2015-06-01

Authors

Galac, SaraORCID 0000-0002-4831-4995ISNI 0000000393573977
Wilson, David B

Editors

Advisors

Supervisors

Document Type

Part of book
Open Access logo

License

taverne

Abstract

This comparative review highlights animal models of adrenocortical neoplasia useful either for mechanistic studies or translational research. Three model species-mouse, ferret, and dog-are detailed. The relevance of each of these models to spontaneous and inherited adrenocortical tumors in humans is discussed.

Keywords

Adrenal cortex, Cushing syndrome, Dog, Endocrine tumor, Ferret, Gonadectomy, Mouse, Taverne

Citation

Galac, S & Wilson, D B 2015, Animal Models of Adrenocortical Tumorigenesis. in Endocrinology and Metabolism Clinics of North America. Endocrinology and Metabolism Clinics of North America, vol. 44, W.B. Saunders Ltd, pp. 297-310. https://doi.org/10.1016/j.ecl.2015.02.003