Eczeem en antimicrobiële therapie

Abstract

Most patients with atopic dermatitis (AD) are colonized with Staphylococcus aureus. Moreover, infection with S. aureus is more common in AD patients compared to normal controls. Although a role for S.aureus in the pathogenesis AD has long been accepted, the exact mechanisms by which S. aureus interacts with the skin immune system need to be elucidated. Multiple factors, including superantigens may play an important role. New therapies targeting the cross-talk between microbes and the host, or directly targeting of microbiome will be discussed.