Log In

A Long-Distance Chromatin Affair

Files

Chromatin.pdf (211.33 KB)

Publication date

2015-08-27

Authors

Denker, Annette
de Laat, WouterISNI 0000000388639337

Editors

Advisors

Supervisors

DOI

https://doi.org/10.1016/j.cell.2015.08.022

Document Type

Article

Metadata

Show full item record

Collections

UMC Repository
Open Access logo

License

taverne

Abstract

Changes in transcription factor binding sequences result in correlated changes in chromatin composition locally and at sites hundreds of kilobases away. New studies demonstrate that this concordance is mediated via spatial chromatin interactions that constitute regulatory modules of the human genome.

Keywords

Chromatin, Chromosomes, Human, Female, Gene Expression Regulation, Genetic Variation, Genome, Human, Human Genome Project, Humans, Male, Taverne, Comment, Journal Article, Research Support, Non-U.S. Gov't

Citation

Denker, A & de Laat, W 2015, 'A Long-Distance Chromatin Affair', Cell, vol. 162, no. 5, pp. 942-3. https://doi.org/10.1016/j.cell.2015.08.022

URI

https://dspace.library.uu.nl/handle/1874/333239