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Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma

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Publication date

1994

Authors

HILL, FWG
Rutten, VictorORCID 0000-0002-6171-1805ISNI 0000000392221478
HOYER, MH
KLEIN, WR
KOTEN, JW
STEERENBERG, PA
RUITENBERG, EJ
DENOTTER, W

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DOI

https://doi.org/10.1007/BF01517180

Document Type

Article

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Utrecht University Repository

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Abstract

Thirty cows from a pedigree Friesian dairy herd with bovine vulva papilloma and carcinoma were treated by intralesional injections of live bacillus Calmette-Guérin (BCG). This treatment induced total regression of all of six carcinomas. Whilst, after treatment, limited regression was also observed in advanced papillomas, BCG has little or no effect on the early stages of papillomas. This is the first study of BCG therapy in this type of cancer.

Keywords

BCG, Bovine vulval papilloma-carcinoma, Immunotherapy, Immunology and Allergy, Immunology, Oncology, Cancer Research, SDG 3 - Good Health and Well-being

Citation

HILL, FWG, RUTTEN, VPMG, HOYER, MH, KLEIN, WR, KOTEN, JW, STEERENBERG, PA, RUITENBERG, EJ & DENOTTER, W 1994, 'Local bacillus Calmette-Guérin therapy for bovine vulval papilloma and carcinoma', Cancer Immunology Immunotherapy, vol. 39, no. 1, pp. 49-52. https://doi.org/10.1007/BF01517180

URI

https://dspace.library.uu.nl/handle/1874/468476