Log In

Who Is in the Driver's Seat: Tracing Cancer Genes Using CRISPR-Barcoding

Files

65_main.pdf (735.67 KB)
How and where to find an Open Access version of this publication?

Publication date

2016-08-04

Authors

Drost, Jarno
Clevers, HansISNI 0000000043961208

Editors

Advisors

Supervisors

DOI

https://doi.org/10.1016/j.molcel.2016.07.013

Document Type

Article

Metadata

Show full item record

Collections

UMC Repository

License

Abstract

Intratumor heterogeneity is thought to be the driving force of tumor evolution and therapy resistance. Yet tools to study these processes are limited. In this issue, Guernet et al. (2016) devised clustered regularly interspaced short palindromic repeats (CRISPR)-barcoding to functionally annotate specific mutations and study clonal evolution in heterogeneous cell populations.

Keywords

Molecular Biology, Cell Biology, Journal Article

Citation

Drost, J & Clevers, H 2016, 'Who Is in the Driver's Seat : Tracing Cancer Genes Using CRISPR-Barcoding', Molecular Cell, vol. 63, no. 3, pp. 352-354. https://doi.org/10.1016/j.molcel.2016.07.013

URI

http://hdl.handle.net/1874/346651