Hormone replacement in survivors of childhood cancer and brain tumors: safety and controversies

Publication date

2022-12-13

Authors

van Roessel, Ichelle
Bakker, B.ORCID 0000-0003-0229-1123
van Santen, Hanneke MORCID 0000-0002-6773-6931ISNI 0000000387710357
Chemaitilly, Wassim

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

cc_by

Abstract

Childhood cancer survivors are at risk for developing endocrine disorders, including deficits in growth hormone, thyroid hormone and sex hormones. The influence these hormones have on cell growth and metabolism has raised concerns regarding the safety of their use as treatments in survivors of childhood cancer and brain tumors. This manuscript offers a summary of current knowledge, controversies and areas for future research pertaining to this area.

Keywords

childhood cancer, childhood brain tumors, growth hormone, hypothyroidism, hypogonadism, Journal Article, Review

Citation

van Roessel, I M A A, Bakker, B, van Santen, H M & Chemaitilly, W 2022, 'Hormone replacement in survivors of childhood cancer and brain tumors : safety and controversies', Endocrine connections, vol. 12, no. 1. https://doi.org/10.1530/EC-22-0382