Epidemiology and molecular typing of multidrug-resistant bacteria in tertiary hospitals and nursing homes in Flanders, Belgium
Publication date
2024-01
Authors
van Kleef-van Koeveringe, Stefanie
Matheeussen, Veerle
Schuermans, Annette
De Koster, Sien
Perales Selva, Natascha
Jansens, Hilde
De Coninck, Dieter
De Bruyne, Katrien
Mensaert, Klaas
Kluytmans-Van Den Bergh, M
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Document Type
Article
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Abstract
This study aimed to map MDRO carriage and potential transmission within and between three Flemish tertiary care hospitals and their neighbouring nursing homes. A cross-sectional MDRO prevalence survey was organized between October 2017 and February 2019. Perianal swabs were cultured for detection of MDRO. Determination of clonal relatedness based on wgMLST allelic profiles was performed. The prevalence of MDRO in Belgian hospitals and NHs is on the rise, compared to previous studies, and transmission in and between institutions is observed. These results re-emphasize the need for a healthcare network-wide infection prevention strategy in which WGS of MDRO strains can be supportive.
Keywords
MDRO, Molecular typing, Screening, Transmission, wgMLST, Whole-genome sequencing, Microbiology (medical), Infectious Diseases, Journal Article
Citation
van Kleef-van Koeveringe, S, Matheeussen, V, Schuermans, A, De Koster, S, Perales Selva, N, Jansens, H, De Coninck, D, De Bruyne, K, Mensaert, K, Kluytmans-van den Bergh, M, Kluytmans, J, Goossens, H, Dhaeze, W & Leroux-Roels, I 2024, 'Epidemiology and molecular typing of multidrug-resistant bacteria in tertiary hospitals and nursing homes in Flanders, Belgium', European Journal of Clinical Microbiology and Infectious Diseases, vol. 43, no. 1, pp. 187-194. https://doi.org/10.1007/s10096-023-04699-2