Clinical evidence on haemodiafiltration
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Publication date
2018-10-01
Authors
Blankestijn, Peter J
Grooteman, Muriel P.
Nube, Menso J.
Bots, Michiel
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Document Type
Article
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Abstract
Haemodiafiltration (HDF) combines diffusive and convective solute removal in a single treatment session. HDF provides a greater removal of higher molecular weight uraemic retention solutes than conventional high-flux haemodialysis (HD). Recently completed randomized clinical trials suggest better patient survival with online HDF. The treatment is mainly used in Europe and Japan. This review gives a brief overview of the presently available evidence of the effects of HDF on clinical end points, it speculates on possible mechanisms of a beneficial effect of HDF as compared with standard HD and ends with some perspectives for the future.
Keywords
chronic hemodialysis, clinical outcome, hemodiafiltration, online hemodiafiltration, review, Nephrology, Transplantation
Citation
Blankestijn, P J, Grooteman, M P, Nube, M J & Bots, M L 2018, 'Clinical evidence on haemodiafiltration', Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, vol. 33, no. suppl_3, pp. iii53-iii58. https://doi.org/10.1093/ndt/gfy218, https://doi.org/10.1093/ndt/gfy218