Imaging of pediatric great vessel stents: Computed tomography or magnetic resonance imaging?

Publication date

2017-01-01

Authors

den Harder, Annemarie M.
Suchá, D.
van Hamersvelt, Robbert W
Budde, Ricardo P. J.ISNI 0000000392898112
de Jong, Pim AORCID 0000-0003-4840-6854ISNI 0000000395539334
Schilham, Arnold M. R.ISNI 0000000391935778
Bos, CORCID 0000-0002-9246-3242ISNI 0000000388845122
Breur, Johannes M P JISNI 0000000395622111
Leiner, TimORCID 0000-0003-1885-5499ISNI 0000000390698205

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

Abstract

BACKGROUND: Complications might occur after great vessel stent implantation in children. Therefore follow-up using imaging is warranted. PURPOSE: To determine the optimal imaging modality for the assessment of stents used to treat great vessel obstructions in children. MATERIAL AND METHODS: Five different large vessel stents were evaluated in an in-vitro setting. All stents were expanded to the maximal vendor recommended diameter (20mm; n = 4 or 10mm; n = 1), placed in an anthropomorphic chest phantom and imaged with a 256-slice CT-scanner. MRI images were acquired at 1.5T using a multi-slice T2-weighted turbo spin echo, an RF-spoiled three-dimensional T1-weighted Fast Field Echo and a balanced turbo field echo 3D sequence. Two blinded observers assessed stent lumen visibility (measured diameter/true diameter *100%) in the center and at the outlets of the stent. Reproducibility of diameter measurements was evaluated using the intraclass correlation coefficient for reliability and 95% limits of agreement for agreement analysis. RESULTS: Median stent lumen visibility was 88 (IQR 86-90)% with CT for all stents at both the center and outlets. With MRI, the T2-weighted turbo spin echo sequence was preferred which resulted in 82 (78-84%) stent lumen visibility. Interobserver reliability and agreement was good for both CT (ICC 0.997, mean difference -0.51 [-1.07-0.05] mm) and MRI measurements (ICC 0.951, mean difference -0.05 [-2.52 --2.41] mm). CONCLUSION: Good in-stent lumen visibility was achievable in this in-vitro study with both CT and MRI in different great vessel stents. Overall reliability was good with clinical acceptable limits of agreement for both CT and MRI. However, common conditions such as in-stent stenosis and associated aneurysms were not tested in this in-vitro study, limiting the value of the in-vitro study.

Keywords

General Medicine, General Biochemistry,Genetics and Molecular Biology, General Agricultural and Biological Sciences, Journal Article

Citation

den Harder, A M, Suchá, D, van Hamersvelt, R W, Budde, R P J, de Jong, P A, Schilham, A M R, Bos, C, Breur, J M P J & Leiner, T 2017, 'Imaging of pediatric great vessel stents : Computed tomography or magnetic resonance imaging?', PLoS ONE [E], vol. 12, no. 1, e0171138. https://doi.org/10.1371/journal.pone.0171138