Engineered heart tissue patches: A milestone in cardiac regenerative medicine

Publication date

2025-04-03

Authors

van Mil, AlainORCID 0000-0001-9906-5047ISNI 0000000388487943
Janssen, Jasmijn
van Rooij, EvaISNI 0000000390646771

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taverne

Abstract

Researchers have demonstrated that a stem cell-derived heart muscle patch can safely remuscularize failing hearts.1 Published in Nature, the study shows successful long-term cardiac integration of a patch in a primate model and a human patient with no adverse effects. This breakthrough marks a major step toward regenerative therapies for advanced heart failure.

Keywords

Animals, Heart Failure/therapy, Heart/physiology, Humans, Myocardium/cytology, Regenerative Medicine/methods, Tissue Engineering/methods, Taverne, Journal Article

Citation

van Mil, A, Janssen, J & van Rooij, E 2025, 'Engineered heart tissue patches : A milestone in cardiac regenerative medicine', Cell stem cell, vol. 32, no. 4, pp. 505-507. https://doi.org/10.1016/j.stem.2025.02.012