Investigating the use of comprehensive motion monitoring for intrafraction 3D drift assessment of hypofractionated prostate cancer patients on a 1.5T magnetic resonance imaging radiotherapy system

Publication date

2024-07

Authors

Tsekas, G
Zachiu, Cornel
Bol, G HORCID 0000-0002-7393-167XISNI 0000000392489626
van den Dobbelsteen, Madelon
Meijers, Lieke T.C.
van Lier, Astrid L H M WORCID 0000-0002-2150-9776
de Boer, Johannes C J
Raaymakers, Bas WORCID 0000-0002-8036-6808ISNI 0000000392005337

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Article

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Abstract

This work investigates the use of a multi-2D cine magnetic resonance imaging-based comprehensive motion monitoring (CMM) system for the assessment of prostate intrafraction 3D drifts. The data of six healthy volunteers were analyzed and the values of a clinically-relevant registration quality factor metric exported by CMM were presented. Additionally, the CMM-derived prostate motion was compared to a 3D-based reference and the 2D-3D tracking agreement was reported. Due to the low quality of SI motion tracking (often >2 mm tracking mismatch between anatomical planes) we conclude that further improvements are desirable prior to clinical introduction of CMM for prostate drift corrections.

Keywords

Intrafraction drift correction, Intrafraction motion, Motion management, MR-guided radiotherapy, Radiation, Oncology, Radiology Nuclear Medicine and imaging

Citation

Tsekas, G, Zachiu, C, Bol, G H, van den Dobbelsteen, M, Meijers, L T C, van Lier, A L H M W, de Boer, J C J & Raaymakers, B W 2024, 'Investigating the use of comprehensive motion monitoring for intrafraction 3D drift assessment of hypofractionated prostate cancer patients on a 1.5T magnetic resonance imaging radiotherapy system', Physics and Imaging in Radiation Oncology, vol. 31, 100596. https://doi.org/10.1016/j.phro.2024.100596