Prolonged carriage and potential onward transmission of carbapenemase-producing Enterobacteriaceae in Dutch travelers
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Publication date
2016-07-01
Authors
Van Hattem, Jarne M.
Arcilla, Maris S.
Bootsma, Martin C. J.
Van Genderen, Perry J.
Goorhuis, Abraham
Grobusch, Martin P.
Molhoek, Nicky
Oude Lashof, Astrid M L
Schultsz, Constance
Stobberingh, Ellen E.
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Document Type
Article
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taverne
Abstract
Aim: The aim was to study acquisition and persistence of carbapenemase-producing Enterobacteriaceae (CPE) among travelers. Materials & methods: Stools from 2001 travelers and 215 nontraveling household members, collected before and immediately post-travel as well as 1, 3, 6 and 12 months upon return, were screened for CPE. Results: Five travelers, all visiting Asia outside the Indian subcontinent, acquired CPE. One traveler persistently carried the same OXA-244 CPE up to 6 months post-travel. Three months after travel, her co-traveling spouse also became positive for this OXA-244 CPE strain, suggesting clonal transmission within this household. Conclusion: Acquisition of CPE is not restricted to travelers to the Indian subcontinent and/or to travelers seeking healthcare during travel and can persist up to at least 6 months post-travel.
Keywords
carbapenemases, Enterobacteriaceae, transmission, travel, Taverne, Microbiology, Microbiology (medical), Journal Article, Clinical Trial, Multicenter Study
Citation
Van Hattem, J M, Arcilla, M S, Bootsma, M C J, Van Genderen, P J, Goorhuis, A, Grobusch, M P, Molhoek, N, Oude Lashof, A M L, Schultsz, C, Stobberingh, E E, Verbrugh, H A, De Jong, M D, Melles, D C & Penders, J 2016, 'Prolonged carriage and potential onward transmission of carbapenemase-producing Enterobacteriaceae in Dutch travelers', Future microbiology, vol. 11, no. 7, pp. 857-864. https://doi.org/10.2217/fmb.16.18