Emergence of candida auris in brazil in a covid-19 intensive care unit
Publication date
2021-03
Authors
de Almeida, João N.
Francisco, Elaine C.
Hagen, Ferry
Brandão, Igor B.
Pereira, Felicidade M.
Presta Dias, Pedro H.
de Miranda Costa, Magda M.
de Souza Jordão, Regiane T.
de Groot, Theun
Colombo, Arnaldo L.
Editors
Advisors
Supervisors
Document Type
Article
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Abstract
In December 2020, Candida auris emerged in Brazil in the city of Salvador. The first two C. auris colonized patients were in the same COVID-19 intensive care unit. Antifungal susceptibility testing showed low minimal inhibitory concentrations of 1 µg/mL, 2 µg/mL, 0.03 µg/L, and 0.06 µg/mL for amphotericin B, fluconazole, voriconazole, and anidulafungin, respectively. Microsatel-lite typing revealed that the strains are clonal and belong to the South Asian clade C. auris. The travel restrictions during the COVID-19 pandemic and the absence of travel history among the colonized patients lead to the hypothesis that this species was introduced several months before the recognition of the first case and/or emerged locally in the coastline Salvador area.
Keywords
Brazil, Candida auris, COVID-19, Intensive care, Ecology, Evolution, Behavior and Systematics, Plant Science, Microbiology (medical)
Citation
de Almeida, J N, Francisco, E C, Hagen, F, Brandão, I B, Pereira, F M, Presta Dias, P H, de Miranda Costa, M M, de Souza Jordão, R T, de Groot, T & Colombo, A L 2021, 'Emergence of candida auris in brazil in a covid-19 intensive care unit', Journal of Fungi, vol. 7, no. 3, 220. https://doi.org/10.3390/jof7030220