Separable mixing: The general formulation and a particular example focusing on mask efficiency
Publication date
2023
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Abstract
The aim of this short note is twofold. First, we formulate the general Kermack-McKendrick epidemic model incorporating static heterogeneity and show how it simplifies to a scalar Renewal Equation (RE) when separable mixing is assumed. A key general feature is that all information about the heterogeneity is encoded in one nonlinear real valued function of a real variable. Next, we specialize the model ingredients so that we can study the efficiency of mask wearing as a non-pharmaceutical intervention to reduce the spread of an infectious disease. Our main result affirms that the best way to protect the population as a whole is to protect yourself. This qualitative insight was recently derived in the context of an SIR network model. Here, we extend the conclusion to proportionate mixing models incorporating a general function describing expected infectiousness as a function of time since infection.
Keywords
epidemic model, heterogeneity, Kermack-McKendrick, mask efficiency, separable mixing, Modelling and Simulation, General Agricultural and Biological Sciences, Computational Mathematics, Applied Mathematics
Citation
Bootsma, M C J, Chan, K M D, Diekmann, O & Inaba, H 2023, 'Separable mixing : The general formulation and a particular example focusing on mask efficiency', Mathematical Biosciences and Engineering, vol. 20, no. 10, pp. 17661-17671. https://doi.org/10.3934/mbe.2023785