Optimization of the convection volume in online post-dilution haemodiafiltration: practical and technical issues
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Publication date
2015-04
Authors
Chapdelaine, Isabelle
De Roij Van Zuijdewijn, Camiel L M
Mostovaya, Ira M
Lévesque, Renée
Davenport, Andrew
Blankestijn, Peter J.
Wanner, Christoph
Nubé, Menso J
Grooteman, Muriel P C
Davenport, A
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Abstract
In post-dilution online haemodiafiltration (ol-HDF), a relationship has been demonstrated between the magnitude of the convection volume and survival. However, to achieve high convection volumes (>22 L per session) detailed notion of its determining factors is highly desirable. This manuscript summarizes practical problems and pitfalls that were encountered during the quest for high convection volumes. Specifically, it addresses issues such as type of vascular access, needles, blood flow rate, recirculation, filtration fraction, anticoagulation and dialysers. Finally, five of the main HDF systems in Europe are briefly described as far as HDF prescription and optimization of the convection volume is concerned.
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Chapdelaine, I, de Roij van Zuijdewijn, C L M, Mostovaya, I M, Lévesque, R, Davenport, A, Blankestijn, P J, Wanner, C, Nubé, M J, Grooteman, M P C, Davenport, A, Basile, C, Locatelli, F, Maduell, F, Mitra, S, Ronco, C, Shroff, R, Tattersall, J, Wanner, C & EUDIAL Group 2015, 'Optimization of the convection volume in online post-dilution haemodiafiltration : practical and technical issues', Clinical Kidney Journal, vol. 8, no. 2, pp. 191-198. https://doi.org/10.1093/ckj/sfv003