Iron Deficiency, Anemia and Mortality in Renal Transplant Recipients
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Publication date
2016-11
Authors
Eisenga, Michele F.
Minovic, Isidor
Berger, Stefan P
Kootstra-Ros, Jenny E.
van den Berg, Else
Riphagen, Ineke J.
Navis, Gerjan J.
Van der Meer, Peter
Bakker, Stephan J. L.
Gaillard, Carlo A J M
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Abstract
Anemia, iron deficiency anemia (IDA), and iron deficiency (ID) are highly prevalent in renal transplant recipients (RTR). Anemia is associated with poor outcome, but the role of ID is unknown. Therefore, we aimed to investigate the association of ID, irrespective of anemia, with all-cause mortality in RTR. Cox regression analyses were used to investigate prospective associations. In 700 RTR, prevalences of anemia, IDA, and ID were 34%, 13%, and 30%, respectively. During follow-up for 3.1 (2.7-3.9) years, 81 (12%) RTR died. In univariable analysis, anemia [HR, 1.72 (95% CI: 1.11-2.66), P = 0.02], IDA [2.44 (1.48-4.01), P
Keywords
anemia, iron deficiency, kidney transplantation, mortality, CORONARY-HEART-DISEASE, C-REACTIVE PROTEIN, POSTTRANSPLANTATION ANEMIA, KIDNEY, INFLAMMATION, MANAGEMENT, FAILURE, RISK, METABOLISM, RATIONALE
Citation
Eisenga, M F, Minovic, I, Berger, S P, Kootstra-Ros, J E, van den Berg, E, Riphagen, I J, Navis, G J, Van der Meer, P, Bakker, S J L & Gaillard, C A J M 2016, 'Iron Deficiency, Anemia and Mortality in Renal Transplant Recipients', Transplant International, vol. 29, no. 11, pp. 1176-1183. https://doi.org/10.1111/tri.12821