Post-mortem Magnetic Resonance Imaging of Degenerating and Reorganizing White Matter in Post-stroke Rodent Brain
Publication date
2023-01-31
Authors
Wielenga, Vera H.
Dijkhuizen, Rick M.
van der Toorn, A
Editors
Karamyan, Vardan T.
Stowe, Ann M.
Advisors
Supervisors
Document Type
Part of book
Metadata
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taverne
Abstract
Magnetic resonance imaging (MRI) allows noninvasive and non-destructive imaging of brain tissue. More specifically, the status of white matter fibers can be measured with diffusion-weighted MRI, enabling assessment of structural degeneration or remodeling of white matter tracts in diseased brain. Here, we describe the preparation of post-stroke rodent brain samples for post-mortem high-resolution 3D diffusion-weighted MR imaging, accompanied with guidelines for acquiring and processing the images.
Keywords
Diffusion-weighted MRI, Microstructure, Neuroimaging, Rodent brain, Taverne, Molecular Biology, Genetics
Citation
Wielenga, V H, Dijkhuizen, R M & Van der Toorn, A 2023, Post-mortem Magnetic Resonance Imaging of Degenerating and Reorganizing White Matter in Post-stroke Rodent Brain. in V T Karamyan & A M Stowe (eds), Neural Repair : Methods and Protocols. 1 edn, Methods in Molecular Biology, vol. 2616, Humana New York, pp. 153-168. https://doi.org/10.1007/978-1-0716-2926-0_12