Spiking the MERS-coronavirus receptor

Publication date

2013-09

Authors

Bosch, Berend-JanISNI 0000000387346575
Raj, V Stalin
Haagmans, Bart L

Editors

Advisors

Supervisors

Document Type

Article
Open Access logo

License

Abstract

A novel coronavirus, the Middle East respiratory syndrome coronavirus, recently emerged through zoonotic transmission, causing a severe lower respiratory tract infection in humans. In two recent papers, one published in Cell Research, the crystal structure of the viral receptor-binding domain in complex with the host CD26/dipeptidyl peptidase 4 receptor has now been characterized.

Keywords

Animals, Coronavirus, Dipeptidyl Peptidase 4, Humans, Receptors, Virus, Viral Proteins, Virus Attachment, Coronacrisis-Taverne

Citation

Bosch, B J, Raj, V S & Haagmans, B L 2013, 'Spiking the MERS-coronavirus receptor', Cell Research, vol. 23, no. 9, pp. 1069-70. https://doi.org/10.1038/cr.2013.108