Mode of action of protein synthesis initiation factor eIF-1 from rabbit reticulocytes
Publication date
1980-07-14
Authors
Thomas, A.
Spaan, W.
Steeg, H. van
Voorma, H.O.
Benne, R.
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
Abstract
Initiation of eukaryotic protein synthesis is mediated
by a set of protein factors, purified using predominantly
rabbit reticulocytes and Krebs II
ascites cells. At least 8 initiation factors with Mr
15000-700000 could be described. This elaborate
work was followed by the functional characterization
of the individual factors which provided considerable
insight in the specific contribution of each factor
during the assembly of an initiation complex,
reviewed.
Keywords
Initiation of eukaryotic protein synthesis is mediated
by a set of protein factors, purified using predominantly
rabbit reticulocytes and Krebs II
ascites cells. At least 8 initiation factors with Mr
15 000-700 000 could be described. This elaborate
work was followed by the functional characterization
of the individual factors which provided considerable
insight in the specific contribution of each factor
during the assembly of an initiation complex,
reviewed.