Factor VIII-related antigen in canine hemophilia and von Willebrand's disease: Variation when measured with different agaroses

Abstract

The source of agarose used in the Laurell electroimmunoassay was found to produce variations in the factor VIII-related antigen levels of plasmas from dogs with von Willebrand's disease and hemophilia A. Similar artifactual variations in antigen were not observed for normal canine plasmas.