On the variability of the salting-out curves of proteins of normal human plasma and serum

Abstract

Salting-out curves of proteins of normal human plasma reflect the influence of a number of other factors besides the protein composition: the manner of obtaining the blood, the nature of the anti-coagulant used, the non-protein components of the plasma.

Diagrams of serum and plasma obtained from one sample of blood are mutually different.

The diagrams of dialyzed plasma, always prepared in the same manner, also changes with time in one individual, while no two persons have the same diagram. So the circulating plasma proteins appear to be in a highly dynamic state.