Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex
Publication date
2018-01-01
Authors
Abdulghani, Sahar
Moretti, Felipe
Nikkels, Peter G J
Khung-Savatovsky, Suonavy
Hurteau-Miller, Julie
Grynspan, David
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Supervisors
Document Type
Article
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taverne
Abstract
We describe a case of a pregnancy complicated by early onset asymmetric growth restriction with anhydramnios with termination occurring at 21 weeks. Fetal autopsy showed demineralization of bones and renal tubular dysgenesis. Placental pathology showed features of massive perivillous fibrin deposition and chronic histiocytic intervillositis. We review prior documentation of this association and briefly discuss potential pathogenesis.
Keywords
chronic intervillosistis, fetal, intrauterine growth restriction, massive perivillous fibrin, placenta, renal tubular dysgenesis, Taverne, Pediatrics, Perinatology, and Child Health, Pathology and Forensic Medicine
Citation
Abdulghani, S, Moretti, F, Nikkels, P G J, Khung-Savatovsky, S, Hurteau-Miller, J & Grynspan, D 2018, 'Growth Restriction, Osteopenia, Placental Massive Perivillous Fibrin Deposition With (or Without) Intervillous Histiocytes and Renal Tubular Dysgenesis—An Emerging Complex', Pediatric and Developmental Pathology, vol. 21, no. 1, pp. 91-94. https://doi.org/10.1177/1093526617697061