The Prediagnostic General Practitioners' Pathway of Gastrointestinal Stromal Tumor Patients: A Real-World Data Study

Publication date

2025-04-22

Authors

Holthuis, Emily I
Slijkhuis, Verena
van der Graaf, Winette T A
Drabbe, Cas
van Houdt, Winan J
Schrage, Yvonne M
Olde Hartman, Tim C
Uijen, Annemarie
Steeghs, NeeltjeORCID 0000-0003-2989-2279
Bos, Isabelle

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Article

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Abstract

Gastrointestinal stromal tumors (GISTs) are rare digestive tract cancers that are often challenging to diagnose early due to nonspecific symptoms. General practitioners (GPs) are typically the first to evaluate these symptoms, making them crucial for early detection. However, limited research has examined how GIST patients seek medical care before diagnosis. This study investigates GP visits, reported diagnoses, and prescribed medications in the year preceding a GIST diagnosis. Our findings indicate that GIST patients attend more frequent GP visits, with a significant increase in the months leading up to diagnosis, often due to digestive issues and anemia. Future research should analyze GP records in greater detail to refine strategies for earlier recognition and intervention, eventually leading to faster diagnosis and better patient outcomes.

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Journal Article

Citation

Holthuis, E I, Slijkhuis, V, van der Graaf, W T A, Drabbe, C, van Houdt, W J, Schrage, Y M, Olde Hartman, T C, Uijen, A, Steeghs, N, Bos, I, Heins, M & Husson, O 2025, 'The Prediagnostic General Practitioners' Pathway of Gastrointestinal Stromal Tumor Patients : A Real-World Data Study', Cancers, vol. 17, no. 9, 1391. https://doi.org/10.3390/cancers17091391