Characteristics and outcome of children with renal cell carcinoma: A narrative review

Publication date

2020-07-03

Authors

van der Beek, Justine
Geller, James I.
de Krijger, RonaldORCID 0000-0001-6871-1296ISNI 0000000393710847
Graf, Norbert
Pritchard-Jones, Kathy
Drost, Jarno
Verschuur, Arnauld C.
Murphy, Dermot
Ray, Satyajit
Spreafico, Filippo

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Abstract

Pediatric renal cell carcinoma (RCC) is a rare type of kidney cancer, most commonly occurring in teenagers and young adolescents. Few relatively large series of pediatric RCC have been reported. Knowledge of clinical characteristics, outcome and treatment strategies are often based on the more frequently occurring adult types of RCC. However, published pediatric data suggest that clinical, molecular and histological characteristics of pediatric RCC differ from adult RCC. This paper summarizes reported series consisting of ≥10 RCC pediatric patients in order to create an up-to-date overview of the clinical and histopathological characteristics, treatment and outcome of pediatric RCC patients.

Keywords

Outcome, Pediatric, Renal cell carcinoma, Survival, Treatment, treatment, renal cell carcinoma, survival, outcome, pediatric, Oncology, Cancer Research, Review, Journal Article

Citation

van der Beek, J N, Geller, J I, de Krijger, R R, Graf, N, Pritchard-Jones, K, Drost, J, Verschuur, A C, Murphy, D, Ray, S, Spreafico, F, Dzhuma, K, Littooij, A S, Selle, B, Tytgat, G A M & van den Heuvel-Eibrink, M M 2020, 'Characteristics and outcome of children with renal cell carcinoma : A narrative review', Cancers, vol. 12, no. 7, 1776, pp. 1-26. https://doi.org/10.3390/cancers12071776