The structure and expression of normal and abnormal globin genes
Publication date
1979
Authors
Bernards, R.A.
Flavell, R.A.
Grosveld, G.C.
Grosveld, F.G.
Kooter, J.M.
Boer, E. de
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Part of book or chapter of book
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Abstract
Most mammalian genes are present as a single
copy per haploid genome and hence comprise only
about one part in 10⁶ of the total nuclear DNA.
This fact impeded work on single-copy genes, but
recently recombinant DNA technology
and sensitive gene mapping has led to the
elucidation of the structure of a number of
eukaryotic genes.