Remaining Challenges in the Treatment of Relapsed Wilms Tumor: Children's Oncology Group and International Society of Paediatric Oncology Perspectives
Publication date
2025-08
Authors
Sutton, Kathryn S
Walz, Amy L
Groenendijk, Alissa
Murphy, Andrew J
Pater, Luke
Janssens, Geert O.
Brzezinski, Jack
Mullen, Elizabeth A
Spreafico, Filippo
Godzinski, Jan
Editors
Advisors
Supervisors
Document Type
Article
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taverne
Abstract
Wilms tumor (WT) is the most common pediatric renal tumor, and with multidisciplinary treatment overall outcomes are excellent. However, a small subset of patients with WT will relapse. The ideal treatment of relapsed WT is yet to be defined. Ongoing studies through the Children's Oncology Group Renal Tumors Committee (COG-RTC) and the International Society of Paediatric Oncology Renal Tumor Study Group (SIOP-RTSG) aim to improve risk stratification and treatment strategies. Members met at the SIOP 55th Annual Congress 2023 to outline available data and knowledge gaps and develop future research priorities.
Keywords
Wilms tumor, renal, solid, tumors, Taverne, Pediatrics, Perinatology, and Child Health, Hematology, Oncology
Citation
Sutton, K S, Walz, A L, Groenendijk, A, Murphy, A J, Pater, L, Janssens, G O, Brzezinski, J, Mullen, E A, Spreafico, F, Godzinski, J, van der Beek, J, HWA Wijnen, M, van den Heuvel-Eibrink, M M, Pachl, M, Graf, N, Ehrlich, P F, Furtwangler, R, Brok, J & Geller, J 2025, 'Remaining Challenges in the Treatment of Relapsed Wilms Tumor : Children's Oncology Group and International Society of Paediatric Oncology Perspectives', Pediatric Blood & Cancer, vol. 72, no. 8, e31790. https://doi.org/10.1002/pbc.31790