Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac
Publication date
2025-01
Authors
Borman, Pim
Uijtewaal, Prescilla
Snyder, Jeffrey
Allen, Bryan
Atienza, Caiden K.
Woodhead, Peter L.
Hyer, Daniel E.
Raaymakers, Bas W
Fast, Martin F
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
cc_by
Abstract
Intensity-modulated radiotherapy (IMRT) in combination with magnetic resonance imaging (MRI)-guided gated delivery represents the latest development in the treatment of abdominothoracic tumours on MR-linac. In contrast, volumetric-modulated arc therapy (VMAT) is typically used on conventional linacs due to its superior delivery efficiency and speed. Non-inferior VMAT plans were created in a research treatment planning system for eight lung cancer patients previously treated on an MR-linac. VMAT plans were delivered on a moving dosimeter using respiratory multi-leaf collimator (MLC) tracking. VMAT with MLC tracking achieved an average 2%/2 mm local gamma pass rate of 93% relative to planned dose with a delivery efficiency of 83%.
Keywords
Lung cancer, MLC tracking, MR-linac, VMAT, Radiation, Oncology, Radiology Nuclear Medicine and imaging
Citation
Borman, P T S, Uijtewaal, P, Snyder, J, Allen, B, Atienza, C K, Woodhead, P, Hyer, D E, Raaymakers, B W & Fast, M F 2025, 'Demonstration of motion-compensated volumetric modulated arc radiotherapy on an MR-linac', Physics and Imaging in Radiation Oncology, vol. 33, 100729. https://doi.org/10.1016/j.phro.2025.100729