Author Correction: Integrative genetic analysis illuminates ALS heritability and identifies risk genes (Nature Communications, (2023), 14, 1, (342), 10.1038/s41467-022-35724-1)

Abstract

Correction to: Nature Communications, published online 20 January 2023 The original version of this article contained errors in Table 2 in the variant_location, cDNA_change, protein_change and dbSNPid columns. The correct version of Table 2 is: (Table presented.) variant_type variant_location cDNA_change protein_change gnomAD_AF ALS cases (n = 9390) Control (n = 4594) MVP CADD dbSNPid missense_variant 22:g.45564104G>A c.46G>A p.Asp16Asn 0.000322851 11 2 0.87 26.5 rs200329756 frameshift_variant 22:g.45564091dupATAGGAATTG c.35_45dupATAGGAATTGG p.Asp16fs NA 1 0 NA NA NA structural 22:g.45564117A>G c.59A>G p.Glu20Gly 4.2e-06 3 0 0.84 26.3 rs1200142847 structural 22:g.45567544C>T c.133C>T p.Arg45Cys 9.68367e-05 9 0 0.89 28.1 rs113634721 missense_variant 22:g.45571835C>T c.214C>T p.Arg72Cys 3.23018e-05 1 0 0.81 23.6 rs781273344 splice_variant 22:g.45574119G>A c.341G>A p.Gly114Asp 0.000419897 3 0 0.73 24.2 rs148003438 missense_variant 22:g.45574245A>G c.467A>G p.Tyr156Cys 2.88367e-05 1 0 0.75 23 rs779406443 missense_variant 22:g.45574601A>G c.823A>G p.Lys275Glu 3.22768e-05 2 0 0.71 23.5 rs753113949 splice_acceptor 22:g.45567480G>C c.70-1G>C NA 3.9-06 1 0 NA 32 rs770658454 missense_variant 22:g.45574313C>G c.535C>G p.Pro179Ala 6.52768e-06 1 0 0.81 22.4 rs763689432 missense_variant 22:g.45580471C>T c.1342C>T p.Arg448Trp 6.52768e-05 1 0 0.91 24 rs777952476 which replaces the previous incorrect version: (Table presented.) variant_type variant_location cDNA_change protein_change gnomAD_AF ALS cases (n = 9390) Control (n = 4594) MVP CADD dbSNPid missense_variant 22:g.45564104G>A c.46G>A p.Asp16Asn 0.000322851 11 2 0.88 26.5 rs200329756 frameshift_variant 22:g.45564091dupATAGGAATTG c.35_45dupATAGGAATTGG p.Asp16fs NA 1 0 NA NA NA structural 22:g.45564117A>G c.59A>G p.Gln20Cys 4.2e-06 3 0 0.86 26.3 rs1200142847 structural 22:g.45567544C>T c.133C>T p.Arg45Cys 9.68367e-05 9 0 0.89 28.1 rs113634721 missense_variant 22:g.45571835C>T c.214C>T p.Arg72Cys 3.23018e-05 1 0 0.81 23.6 rs781273344 splice_variant 22:g.45574119G>A c.341G>A p.Gly114Asp 0.000419897 3 0 0.74 24.2 rs148003438 missense_variant 22:g.45574245A>G c.467A>G p.Tyr156Cys 2.88367e-05 1 0 0.76 23 rs779406443 missense_variant 22:g.45574601A>G c.823A>G p.Lys275Glu 3.22768e-05 2 0 0.71 23.5 rs753113943 splice_acceptor 22:g.45567480G>C c.70-1G>C NA 3.9-06 1 0 NA 32 rs770658454 missense_variant 22:g.45178432C>G c.734C>G p.Pro179Ala 6.52768e-06 1 0 0.81 22.4 rs763689432 missense_variant 22:g.45184590C>T c.1734C>G p.Arg448Trp 6.52768e-05 1 0 0.91 24 rs777952476 In addition, the original version of Fig. 3c showed one variant (Lys275Glu) in an incorrect location and another variant (Arg448Trp) was missing. The correct version of Fig. 3 is: (Figure presented.) which replaces the previous incorrect version: (Figure presented.) This has been corrected in both the PDF and HTML versions of the Article.