Viral evasion of the MHC class I antigen presentation pathway. It's a T(r)AP

Publication date

2020-05-13

Authors

Praest, Thomas Patrique

Editors

Advisors

Wiertz, E.J.H.J.
Lebbink, R.J.

Supervisors

Document Type

Dissertation

Collections

Open Access logo

License

Abstract

Herpesviruses use a broad set of immune modulating mechanisms to escape the immune system; causing lifelong infections with these viruses. In this thesis we discuss newly identified interactions between viral evasins and host proteins and how these evasins influence essential processes in the host.

Keywords

Immune evasion, TAP, Herpesviruses, MHC I, Viruses, antigen presentation

Citation