Viral evasion of the MHC class I antigen presentation pathway. It's a T(r)AP
Publication date
2020-05-13
Authors
Praest, Thomas Patrique
Editors
Advisors
Wiertz, E.J.H.J.
Lebbink, R.J.
Supervisors
Document Type
Dissertation
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Abstract
Herpesviruses use a broad set of immune modulating mechanisms to escape the immune system; causing lifelong infections with these viruses. In this thesis we discuss newly identified interactions between viral evasins and host proteins and how these evasins influence essential processes in the host.
Keywords
Immune evasion, TAP, Herpesviruses, MHC I, Viruses, antigen presentation