Hoe behandel ik het catastrofaal antifosfolipidensyndroom?

Abstract

Catastrophic antiphospholipid syndome is a severe, life threatening disorder with a high mortality rate. It is characterized by progressive multi-organ failure due to vascular occlusion. Adequate identification of patients with CAPS and immediate medical treatment can reduce the mortality rate significantly. Although the clinical presentation of CAPS resembles that of other thrombotic microangiopathies, such as TTP and HUS, treatment of possible CAPS should be started immediately, while awaiting diagnostics. In this article, we will discuss the current status of treatment options of CAPS.