Dilemmas concerning heart procurement in controlled donation after circulatory death

Publication date

2023-07-31

Authors

Kaffka Genaamd Dengler, S EORCID 0000-0002-7407-8703
Vervoorn, MatsORCID 0000-0003-2350-5573
Brouwer, M
de Jonge, J C
van der Kaaij, NielsORCID 0000-0002-3669-5209

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Document Type

Article

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Abstract

With an expanding population at risk for heart failure and the resulting increase in patients admitted to the waiting list for heart transplantation, the demand of viable organs exceeds the supply of suitable donor hearts. Use of hearts after circulatory death has reduced this deficit. Two primary techniques for heart procurement in circulatory death donors have been described: direct procurement and perfusion and thoraco-abdominal normothermic regional perfusion. While the former has been accepted as an option for heart procurement in circulatory death donors, the latter technique has raised some ethical questions in relation to the dead donor rule. In this paper we discuss the current dilemmas regarding these heart procurement protocols in circulatory death donors.

Keywords

controlled donation after circulatory death heart transplantation, determination of death, ethics, ex-situ heart perfusion, thoracoabdominal normothermic regional perfusion, Cardiology and Cardiovascular Medicine

Citation

Kaffka Genaamd Dengler, S E, Vervoorn, M T, Brouwer, M, de Jonge, J & van der Kaaij, N P 2023, 'Dilemmas concerning heart procurement in controlled donation after circulatory death', Frontiers in cardiovascular medicine, vol. 10, 1225543. https://doi.org/10.3389/fcvm.2023.1225543