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Synthetic carbohydrate-based vaccines: Synthesis of an L-glycero-D-manno-heptose antigen-T-epitope-lipopeptide conjugate

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Publication date

1997-11-07

Authors

Reichel, Frank
Ashton, Peter R.
Boons, Geert-JanORCID 0000-0003-3111-5954ISNI 0000000120249047

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DOI

https://doi.org/10.1039/a704127f

Document Type

Article

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Abstract

A facile and highly efficient synthesis of a glycopeptidolipid containing a heptose sugar, a synthetic T-epitope and a synthetic immunoadjuvant is presented which represents an important step towards the development of a fully synthetic vaccine against Neisseria meningitidis.

Keywords

Catalysis, Electronic, Optical and Magnetic Materials, Ceramics and Composites, General Chemistry, Surfaces, Coatings and Films, Metals and Alloys, Materials Chemistry, SDG 3 - Good Health and Well-being

Citation

Reichel, F, Ashton, P R & Boons, G J 1997, 'Synthetic carbohydrate-based vaccines : Synthesis of an L-glycero-D-manno-heptose antigen-T-epitope-lipopeptide conjugate', Chemical Communications, no. 21, pp. 2087-2088. https://doi.org/10.1039/a704127f

URI

http://hdl.handle.net/1874/379412