Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma

Publication date

2016-10-15

Authors

Sparidans, RolfISNI 0000000357085984
Rosing, Hilde
Rood, Johannes J.M.ISNI 0000000493300255
Schellens, JohannesISNI 0000000042971906
Beijnen, JosISNI 0000000140305595

Editors

Advisors

Supervisors

Document Type

Article
Open Access logo

License

taverne

Abstract

Keywords

Afatinib, Erlotinib, Gefitinib, Encorafenib, LC MS/MS, Plasma, Taverne

Citation

Sparidans, R W, Rosing, H, Rood, J J M, Schellens, J H M & Beijnen, J H 2016, 'Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma', Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 1033-1034, pp. 390-398. https://doi.org/10.1016/j.jchromb.2016.09.012