PIPAC Pharmacologic and Clinical Data

Publication date

2024-11

Authors

Cortés-Guiral, Delia
Kranenburg, OnnoORCID 0000-0002-2112-4390ISNI 0000000395167454
Sgarbura, Olivia
Van Der Speeten, Kurt
Taibi, Albdelkader
Hübner, Martin
Yacoov, Almog Ben

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Advisors

Supervisors

Document Type

Article

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License

taverne

Abstract

Pressurized intraperitoneal aerosol chemotherapy (PIPAC) emerged as an innovative intraperitoneal chemotherapy delivery system to overcome the issue of limited efficacy of systemic therapies to induce response in peritoneal malignancies. Promising results for patients with mesothelioma peritonei and peritoneal metastasis from gastric, ovarian, colorectal, pancreatic, and hepatobiliary tumors origin are changing the landscape for patients otherwise just facing palliative treatment. Ongoing trials will shed more light on the actual benefits of PIPAC.

Keywords

clinical results, peritoneal metastasis, pharmacology, PIPAC, Taverne, Surgery, Oncology

Citation

Cortés-Guiral, D, Kranenburg, O, Sgarbura, O, Van Der Speeten, K, Taibi, A, Hübner, M & Yacoov, A B 2024, 'PIPAC Pharmacologic and Clinical Data', Journal of Surgical Oncology, vol. 130, no. 6, pp. 1337-1348. https://doi.org/10.1002/jso.27900