Treatment robustness of total body irradiation with volumetric modulated arc therapy
Publication date
2024-01
Authors
Seravalli, Enrica
Willemsen-Bosman, Mirjam
Zoetelief, Annelies
Roosenboom, Sanne
Harderwijk, Tessa
Krikke, Lean
Bol, G H
Kotte, A. N. T. J.
Huijboom, Eline
van Loon, Karel
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
cc_by
Abstract
This study evaluated the robustness of multi-isocenter Volumetric Modulated Arc Therapy Total Body Irradiation dose distribution in the overlapping region between the head-first and feet-first computed tomography scans, considering the longitudinal isocenter shifts recorded during treatment delivery. For 15 out of 22 patients, the dose distribution in the overlapping region fulfilled all three the robustness criteria. The overlapping region dose distribution of the remaining 7 cases fulfilled two robustness criteria. The dose distribution was found to be robust against daily recorded longitudinal isocenter shifts, as a consequence of the patient position verification procedure, of up to 16 mm.
Keywords
Conformal radiotherapy techniques, Junction, Patient position verification, Robustness, TBI, Total body irradiation, VMAT, Radiation, Oncology, Radiology Nuclear Medicine and imaging
Citation
Seravalli, E, Willemsen-Bosman, M, Zoetelief, A, Roosenboom, S, Harderwijk, T, Krikke, L, Bol, G, Kotte, A, Huijboom, E, van Loon, K & Hoeben, B 2024, 'Treatment robustness of total body irradiation with volumetric modulated arc therapy', Physics and Imaging in Radiation Oncology, vol. 29, 100537. https://doi.org/10.1016/j.phro.2024.100537