Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk

Publication date

2016-08-01

Authors

Van Den Elzen, M. T.
van Os-Medendorp, H.ISNI 000000039585617X
Röckmann, Heike
van Hoffen, Els
Lebens, Ans F M
van Doorn, Helma
Klemans, R. J. B.ISNI 000000039705084X
Bruijnzeel-Koomen, Carla A.ISNI 0000000043719227
Hack, ErikISNI 0000000394998862
Kaufman, Leonard

Editors

Advisors

Supervisors

Document Type

Article

Collections

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License

taverne

Abstract

Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (

Keywords

allergenicity, cow's milk allergy, Hereditary angioedema, intracutaneous test, intradermal testing, rabbit allergy, recombinant human C1 esterase inhibitor, skin prick test, subcutaneous administration, subcutaneous challenge, Taverne, Immunology and Allergy, Immunology, Journal Article

Citation

van den Elzen, M T, van Os-Medendorp, H, Röckmann-Helmbach, H, van Hoffen, E, Lebens, A F M, van Doorn, H, Klemans, R J B, Bruijnzeel-Koomen, C A F M, Hack, C E, Kaufman, L, Relan, A & Knulst, A C 2016, 'Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk', Journal of Allergy and Clinical Immunology, vol. 138, no. 2, pp. 476-481.e1. https://doi.org/10.1016/j.jaci.2016.04.019