Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk
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Publication date
2016-08-01
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taverne
Abstract
Background Recombinant human C1 inhibitor (rhC1INH) for on-demand treatment of hereditary angioedema is purified from milk of transgenic rabbits. It contains low amounts (
Keywords
allergenicity, cow's milk allergy, Hereditary angioedema, intracutaneous test, intradermal testing, rabbit allergy, recombinant human C1 esterase inhibitor, skin prick test, subcutaneous administration, subcutaneous challenge, Taverne, Immunology and Allergy, Immunology, Journal Article
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van den Elzen, M T, van Os-Medendorp, H, Röckmann-Helmbach, H, van Hoffen, E, Lebens, A F M, van Doorn, H, Klemans, R J B, Bruijnzeel-Koomen, C A F M, Hack, C E, Kaufman, L, Relan, A & Knulst, A C 2016, 'Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk', Journal of Allergy and Clinical Immunology, vol. 138, no. 2, pp. 476-481.e1. https://doi.org/10.1016/j.jaci.2016.04.019