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Synthesis and applications of β-aminoethanesulfonyl azides

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Publication date

2006-02-01

Authors

Brouwer, Arwin JISNI 0000000389950741
Merkx, Remco
Dabrowska, Katarzyna
Rijkers, Dirk T SISNI 0000000390501855
Liskamp, Rob M.J.ISNI 0000000393845493

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DOI

https://doi.org/10.1055/s-2006-926273

Document Type

Article

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Abstract

A very efficient method for the synthesis of β-aminoethanesulfonyl azides is descibed. These aliphatic sulfonyl azides are accessible starting from a variety of protected amino acids, including those having functionalized side chains. Furthermore, these sulfonyl azides can be coupled to thio acids, and can be substituted with different aliphatic amines.

Keywords

Amino acid, Sulfonamides, Sulfonyl azide, Sulfonyl chloride, Catalysis, Organic Chemistry

Citation

Brouwer, A J, Merkx, R, Dabrowska, K, Rijkers, D T S & Liskamp, R M J 2006, 'Synthesis and applications of β-aminoethanesulfonyl azides', Synthesis, no. 3, pp. 455-460. https://doi.org/10.1055/s-2006-926273

URI

http://hdl.handle.net/1874/387301