Digitally Designed Bone; A 3D-patient-specific Allograft Shelf for Severe Adolescent Hip Dysplasia: From Digital Design to Clinical Reality-A Conceptual Case Report

Publication date

2025-07-01

Authors

van Bussel, Erik M
Nasrabadi, Jafar
Magré, Joëll
Arbabi, VahidORCID 0000-0003-3347-2891ISNI 0000000419547591
Willemsen, K.ORCID 0000-0002-8237-6321
Kaptein, Bart J
Meij, Bjorn P
Tryfonidou, Marianna A
van der Wal, Bart C.H.
Weinans, HarrieORCID 0000-0002-2275-6170ISNI 0000000393288658

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Article

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Abstract

BACKGROUND: Adolescents with severe dysplasia of the hip regularly undergo a periacetabular osteotomy to prevent pain and early osteoarthritis. Unfortunately, this procedure is not suited for severe dysplasia with a non-congruent-deformed hip joint. The optimal treatment might be a tailor-made biologic optimization of femoral coverage with a shape matching the aberrant anatomy. This study introduces a novel approach using a patient-specific allograft shelf augmentation based on personalized 3D kinematic planning. METHODS: A 17-year-old patient with severe right-sided hip dysplasia underwent 3D CT analysis showing a lateral center-edge angle of -7° and a craniocaudal femoral head coverage of 50%. Using digital augmentation techniques and kinematic simulations, the femoral coverage was optimized while respecting the range of motion. An allograft cortical shelf of a distal femur with a matching surface and curvature as digitally designed was found in the bone bank and implanted at the acetabular rim using patient-specific molds. RESULTS: After uncomplicated implantation of the patient-specific allograft shelf, the lateral center-edge angle and femoral head coverage increased to 18° and 77% while preserving range of motion. A CT scan at 9-month follow-up showed incorporation of the allograft in the native bone with sustained coverage of the weight-bearing area of the patient-specific allograft shelf. CONCLUSION: An acetabular augmentation shelf was digitally designed and implanted using a matching allograft donor in a case of severe hip dysplasia. The excellent and predictable functional and radiologic outcomes suggest that patient-specific allograft bone shelves could be a serious option for adolescents with severe hip dysplasia.

Keywords

Acetabulum/surgery, Adolescent, Allografts, Bone Transplantation/methods, Femur/transplantation, Hip Dislocation/surgery, Humans, Imaging, Three-Dimensional, Male, Osteotomy/methods, Tomography, X-Ray Computed, General Medicine, Journal Article, Case Reports

Citation

van Bussel, E M, Nasrabadi, J, Magré, J, Arbabi, V, Willemsen, K, Kaptein, B J, Meij, B P, Tryfonidou, M A, van der Wal, B C H, Weinans, H H & Sakkers, R J B 2025, 'Digitally Designed Bone; A 3D-patient-specific Allograft Shelf for Severe Adolescent Hip Dysplasia : From Digital Design to Clinical Reality-A Conceptual Case Report', Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews, vol. 9, no. 7, e24.00382. https://doi.org/10.5435/JAAOSGlobal-D-24-00382