The effect of host population heterogeneity on epidemic outbreaks

Publication date

2024-02-05

Authors

Bootsma, MartinISNI 0000000396969686
Chan, Danny
Diekmann, O.ORCID 0000-0003-4695-7601ISNI 0000000108765903
Inaba, Hisashi

Editors

Advisors

Supervisors

Document Type

Article
Open Access logo

License

cc_by

Abstract

In the first part of this paper, we review old and new results about the influence of host population heterogeneity on (various characteristics of) epidemic outbreaks. In the second part we highlight a modelling issue that so far has received little attention: how do contact patterns, and hence transmission opportunities, depend on the size and the composition of the host population? Without any claim on completeness, we offer a range of potential (quasi-mechanistic) submodels. The overall aim of the paper is to describe the state-of-the-art and to catalyse new work.

Keywords

Kermack-McKendrick, epidemic outbreak model, static heterogeneity, final size, contact structures, herd immunity threshold, SDG 3 - Good Health and Well-being

Citation

Bootsma, M, Chan, D, Diekmann, O & Inaba, H 2024, 'The effect of host population heterogeneity on epidemic outbreaks', Mathematics in Applied Sciences and Engineering, vol. 5, no. 1, pp. 1-35. https://doi.org/10.5206/mase/16718