Solving a cold case of haemolysis: Back to the basics
Publication date
2015
Authors
Bijleveld, R.
de Kok, J.
van der Zwaag, Bert
Van Wijk, Richard
Diekman, T.
Editors
Advisors
Supervisors
DOI
Document Type
Article
Metadata
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taverne
Abstract
Membrane disorders comprise an important group of inherited haemolytic anaemias. Diagnostic work-up starts with examination of the blood smear, followed by osmotic gradient ektacytometry. In special cases DNA analysis is performed to confirm the diagnosis. For this purpose a next-generation sequencing-based method has been developed. The combination of these techniques established the correct diagnosis in a case of haemolytic anaemia of unknown cause.
Keywords
Blood smear, Hemolytic anemia, Next generation sequencing, Taverne, Internal Medicine
Citation
Bijleveld, R, de Kok, J, van der Zwaag, B, van Wijk, R & Diekman, T 2015, 'Solving a cold case of haemolysis : Back to the basics', Netherlands Journal of Medicine, vol. 73, no. 2, pp. 86-89.