"Bound" complement in the skin of patients with chronic discoid lupus erythematosus and systemic lupus erythematosus

Abstract

At about the same time and independently of each other, Burnham, Neblett, and Fine (1963), and Cormane (1963) were able to show with the direct immunofluorescent method, using commercially prepared fluoresceinlabelled goat anti-human globulin and fluoresceinlabelled goat anti-human gamma-globulin, a staining of the region of the basal membrane in cryostat sections of skin lesions of patients with lupus erythematosus.