The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease

Publication date

2015-11-01

Authors

Hoffmann, H. J.
Santos, A. F.
Mayorga, C.
Nopp, A.
Eberlein, B.
Ferrer, M.
Rouzaire, P.
Ebo, D. G.
Sabato, V.
Sanz, M. L.

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Abstract

The basophil activation test (BAT) has become a pervasive test for allergic response through the development of flow cytometry, discovery of activation markers such as CD63 and unique markers identifying basophil granulocytes. Basophil activation test measures basophil response to allergen cross-linking IgE on between 150 and 2000 basophil granulocytes in

Keywords

allergy diagnosis, allergy monitoring, basophil activation test, basophil granulocyte, CD63, Immunology, Immunology and Allergy, Journal Article, Review

Citation

Hoffmann, H J, Santos, A F, Mayorga, C, Nopp, A, Eberlein, B, Ferrer, M, Rouzaire, P, Ebo, D G, Sabato, V, Sanz, M L, Pecaric-Petkovic, T, Patil, S U, Hausmann, O V, Shreffler, W G, Korosec, P & Knol, E F 2015, 'The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease', Allergy, vol. 70, no. 11, pp. 1393-1405. https://doi.org/10.1111/all.12698