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Lipid Therapy for Intoxications

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1_s2.0_S019556161630136X_main.pdf (448.06 KB)

Publication date

2017-03-01

Authors

Robben, Joris Henricus
Dijkman, Marieke AnnetISNI 0000000392735970

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DOI

https://doi.org/10.1016/j.cvsm.2016.10.018

Document Type

Article

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taverne

Abstract

This review discusses the use of intravenous lipid emulsion (ILE) in the treatment of intoxications with lipophilic agents in veterinary medicine. Despite growing scientific evidence that ILE has merit in the treatment of certain poisonings, there is still uncertainty on the optimal composition of the lipid emulsion, the dosing, the mechanism of action, and the efficacy. Therefore, a critical view of the clinician on the applicability of this modality in intoxications is still warranted. The use of ILE therapy is advocated as an antidote in cases of intoxications with some lipophilic substances.

Keywords

Emulsion, Fat, ILE, Intralipid, Lipid, Lipid resuscitation therapy, Poisoning, Toxin, Taverne, Small Animals

Citation

Robben, J H & Dijkman, M A 2017, 'Lipid Therapy for Intoxications', Veterinary Clinics of North America - Small Animal Practice, vol. 47, no. 2, pp. 435-450. https://doi.org/10.1016/j.cvsm.2016.10.018

URI

http://hdl.handle.net/1874/360341