Ligand-free copper(I) catalyzed N- and O-arylation of aryl halides
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Publication date
2007
Authors
Sperotto, E.
de Vries, J.G.
van Klink, Gerard P.M.
van Koten, G.
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Abstract
A simple and industrially viable protocol for C–N and C–O coupling is reported here. Arylation of phenol, benzylamine and imidazole with aryl bromides is achieved using ligand-free Cu(I) halide salts in low catalytic amount (2.5 mol %).
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Sperotto, E, de Vries, J G, van Klink, G P M & van Koten, G 2007, 'Ligand-free copper(I) catalyzed N- and O-arylation of aryl halides', Tetrahedron Letters, vol. 48, no. 41, pp. 7366-7370.