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Lipid Droplets Grease Enterovirus Replication

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Lipid_droplets.pdf (1.21 MB)

Publication date

2019-08-14

Authors

Belov, George A
van Kuppeveld, Frank J MISNI 0000000369420196

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DOI

https://doi.org/10.1016/j.chom.2019.07.017

Document Type

Article

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Utrecht University Repository
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Abstract

Replication complexes of (+)RNA viruses of eukaryotes are associated with specialized membranous domains, termed replication organelles. How these structures develop is poorly understood. In a recent Cell paper, Laufman et al. (2019) reveal that enteroviruses recruit lipid droplets to support lipid synthesis required for the structural development of replication organelles.

Keywords

Enterovirus, Enterovirus Infections, Humans, Lipid Droplets, Lipids, Virus Replication, Coronacrisis-Taverne

Citation

Belov, G A & van Kuppeveld, F J M 2019, 'Lipid Droplets Grease Enterovirus Replication', Cell Host & Microbe, vol. 26, no. 2, pp. 149-151. https://doi.org/10.1016/j.chom.2019.07.017

URI

http://hdl.handle.net/1874/384834