EVpedia: A community web portal for extracellular vesicles research

Publication date

2015-01-01

Authors

Kim, Dae Kyum
Lee, Jaewook
Kim, Sae Rom
Choi, Dong Sic
Yoon, Yae Jin
Kim, Ji Hyun
Go, Gyeongyun
Nhung, Dinh
Hong, Kahye
Jang, Su Chul

Editors

Advisors

Supervisors

Document Type

Article

Collections

Open Access logo

License

taverne

Abstract

Motivation: Extracellular vesicles (EVs) are spherical bilayered proteolipids, harboring various bioactive molecules. Due to the complexity of the vesicular nomenclatures and components, online searches for EV-related publications and vesicular components are currently challenging. Results: We present an improved version of EVpedia, a public database for EVs research. This community web portal contains a database of publications and vesicular components, identification of orthologous vesicular components, bioinformatic tools and a personalized function. EVpedia includes 6879 publications, 172 080 vesicular components from 263 high-throughput datasets, and has been accessed more than 65 000 times from more than 750 cities. In addition, about 350 members from 73 international research groups have participated in developing EVpedia. This free web-based database might serve as a useful resource to stimulate the emerging field of EV research.

Keywords

MEMBRANE-VESICLES, PROTEOMIC ANALYSIS, EXOSOMES, MICROPARTICLES, CANCER, CELLS, DELIVERY, PLASMA, PROSTASOMES, EXPRESSION, Taverne, Biochemistry, Molecular Biology, Computational Theory and Mathematics, Computer Science Applications, Computational Mathematics, Statistics and Probability, Journal Article, Research Support, Non-U.S. Gov't

Citation

Kim, D K, Lee, J, Kim, S R, Choi, D S, Yoon, Y J, Kim, J H, Go, G, Nhung, D, Hong, K, Jang, S C, Kim, S H, Park, K S, Kim, O Y, Park, H T, Seo, J H, Aikawa, E, Baj-Krzyworzeka, M, Van Balkom, B W M, Belting, M, Blanc, L, Bond, V, Bongiovanni, A, Borràs, F E, Buée, L, Buzás, E I, Cheng, L, Clayton, A, Cocucci, E, Dela Cruz, C S, Desiderio, D M, Di Vizio, D, Ekström, K, Falcon-Perez, J M, Gardiner, C, Giebel, B, Greening, D W, Christina Gross, J, Gupta, D, Hendrix, A, Hill, A F, Hill, M M, Nolte-'T Hoen, E, Hwang, D W, Inal, J, Jagannadham, M V, Jayachandran, M, Jee, Y K, Jørgensen, M, Kim, K P, Kim, Y K, Kislinger, T, Lässer, C, Lee, D S, Lee, H, Van Leeuwen, J, Lener, T, Liu, M L, Lötvall, J, Marcilla, A, Mathivanan, S, Möller, A, Morhayim, J, Mullier, F, Nazarenko, I, Nieuwland, R, Nunes, D N, Pang, K, Park, J, Patel, T, Pocsfalvi, G, Del Portillo, H, Putz, U, Ramirez, M I, Rodrigues, M L, Roh, T Y, Royo, F, Sahoo, S, Schiffelers, R, Sharma, S, Siljander, P, Simpson, R J, Soekmadji, C, Stahl, P, Stensballe, A, Stepień, E, Tahara, H, Trummer, A, Valadi, H, Vella, L J, Wai, S N, Witwer, K, Yánez-Mó, M, Youn, H, Zeidler, R & Gho, Y S 2015, 'EVpedia : A community web portal for extracellular vesicles research', Bioinformatics, vol. 31, no. 6, pp. 933-939. https://doi.org/10.1093/bioinformatics/btu741