Role of Biomaterials and Controlled Architecture on Tendon/Ligament Repair and Regeneration
Publication date
2020-05-07
Authors
No, Young Jung
Castilho, Miguel
Ramaswamy, Yogambha
Zreiqat, Hala
Editors
Advisors
Supervisors
Document Type
Article
Metadata
Show full item recordCollections
License
taverne
Abstract
Engineering synthetic scaffolds to repair and regenerate ruptured native tendon and ligament (T/L) tissues is a significant engineering challenge due to the need to satisfy both the unique biological and biomechanical properties of these tissues. Long-term clinical outcomes of synthetic scaffolds relying solely on high uniaxial tensile strength are poor with high rates of implant rupture and synovitis. Ideal biomaterials for T/L repair and regeneration need to possess the appropriate biological and biomechanical properties necessary for the successful repair and regeneration of ruptured tendon and ligament tissues.
Keywords
fiber architecture, fiber-reinforced hydrogel, hydrogel, ligaments, synthetic biomaterials, tendons, Taverne, Mechanics of Materials, Mechanical Engineering, General Materials Science, Review, Journal Article
Citation
No, Y J, Castilho, M, Ramaswamy, Y & Zreiqat, H 2020, 'Role of Biomaterials and Controlled Architecture on Tendon/Ligament Repair and Regeneration', Advanced materials, vol. 32, no. 18, 1904511. https://doi.org/10.1002/adma.201904511