Sustained fecal-oral human-to-human transmission following a zoonotic event
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Publication date
2017-01-23
Authors
de Graaf, Miranda
Beck, Relja
Caccio, Simone M
Duim, Birgitta
Fraaij, Pieter LA
Le Guyader, Françoise S
Lecuit, Marc
Le Pendu, Jacques
de Wit, Emmie
Schultsz, Constance
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Document Type
Article
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cc_by_nc_nd
Abstract
Bacterial, viral and parasitic zoonotic pathogens that transmit via the fecal-oral route have a major impact on global health. However, the mechanisms underlying the emergence of such pathogens from the animal reservoir and their persistence in the human population are poorly understood. Here, we present a framework of human-to-human transmission of zoonotic pathogens that considers the factors relevant for fecal-oral human-to-human transmission route at the levels of host, pathogen, and environment. We discuss current data gaps and propose future research directions.
Keywords
SDG 3 - Good Health and Well-being
Citation
de Graaf, M, Beck, R, Caccio, S M, Duim, B, Fraaij, P LA, Le Guyader, F S, Lecuit, M, Le Pendu, J, de Wit, E & Schultsz, C 2017, 'Sustained fecal-oral human-to-human transmission following a zoonotic event', Current Opinion in Virology, vol. 22, pp. 1-6. https://doi.org/10.1016/j.coviro.2016.11.001