A school-based program to prevent depressive symptoms and strengthen well-being among pre-vocational students (Happy Lessons): Results of a randomized controlled trial

Publication date

2025-03

Authors

Rombouts, Marieke
Monshouwer, KarinISNI 0000000388414445
Duinhof, Elisa L.ISNI 0000000463422315
Kraiss, Jannis T.
Shields-Zeeman, LauraORCID 0000-0003-0923-8771ISNI 000000052722081X
Kleinjan, MarloesISNI 000000039442560X

Editors

Advisors

Supervisors

Document Type

Article
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License

taverne

Abstract

Background: Many adolescents experience depressive symptoms, with even higher prevalences among lower-educated Dutch students. Effective prevention programs for these students are scarce but needed. This randomized controlled trial (RCT) investigates the effectiveness of school-based prevention program Happy Lessons (HL) among Dutch pre-vocational students. Methods: Classes within schools were randomized to intervention (n = 124) or waitlist control group (n = 143). Students (n = 267, aged 11 to 15) completed questionnaires at baseline, 3- and 6-month follow-up. The primary outcome was depressive symptoms. Secondary outcomes were well-being and life satisfaction. Linear mixed models were executed, based on the intention-to-treat principle. Explorative analysis of the effect of HL on potential mechanisms such as class and school environmental variables was conducted. Trial registration: Dutch Trial Register NL9732. Results: This study found no statistically significant differences in favor of the intervention group on depressive symptoms (T1: Cohen's d [95 % CI] = -0.21[-0.49;0.07], T2: -0.20 [-0.48;0.08]), well-being (T1: 0.24 [-0.04;0.52], T2: 0.18 [-0.10;0.47]), life satisfaction (T1: 0.03 [-0.25;0.31], T2: 0.10 [-0.18;0.39]), classmate support (T1: -0.20 [-0.48;0.08], T2: -0.14 [-0.43;0.14]), school connectedness (T1: -0.08 [-0.36;0.20], T2: 0.20 [-0.08;0.49]), bullying others (T1: OR[CI] = 0.95 [0.68;1.32], T2: 0.92 [0.66;1.29]) and bullying victimization (T1: OR[CI] = 1.93 [0.73;5.15], T2: 1.61 [0.62;4.20]). Significant moderate effects were found on teacher support in favor of the intervention group at T1 (d[CI] = -0.37 [-0.65;-0.08]) and control group at T2 (d[CI] = 0.35 [0.07;0.64]). Conclusions: Further research should focus on the working mechanisms of school-based depression prevention programs and how to successfully implement these programs in the school context.

Keywords

Depression, Pre-vocational students, Randomized controlled trial, School-based program, Well-being, Public Health, Environmental and Occupational Health, Psychiatry and Mental health, SDG 16 - Peace, Justice and Strong Institutions

Citation

Rombouts, M, Monshouwer, K, Duinhof, E L, Kraiss, J T, Shields-Zeeman, L & Kleinjan, M 2025, 'A school-based program to prevent depressive symptoms and strengthen well-being among pre-vocational students (Happy Lessons) : Results of a randomized controlled trial', Mental Health and Prevention, vol. 37, 200398. https://doi.org/10.1016/j.mhp.2025.200398