Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide
Publication date
2017-12
Authors
van Der Vlist, A.
Snijders, T. J.
Stades, A. M.E.
Spliet, W. G.M.
De Vos, F. Y.F.L.
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Document Type
Article
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taverne
Abstract
A 69-year-old man presented with leptomeningeally metastasised pituitary carcinoma, rapidly progressing despite previous treatment with resection, radiotherapy and cabergoline. The patient received temozolomide chemotherapy, resulting in a complete clinical, radiological and biochemical response after 14 cycles, which has been maintained since then. This case lends further support to the role of temozolomide in refractory pituitary tumours.
Keywords
Pituitary carcinoma, Prolactinoma, Temozolomide, Taverne, Internal Medicine
Citation
van Der Vlist, A, Snijders, T J, Stades, A M E, Spliet, W G M & De Vos, F Y F L 2017, 'Successful treatment of leptomeningeally metastasised pituitary carcinoma with temozolomide', Netherlands Journal of Medicine, vol. 75, no. 10, pp. 451-454.